干扰素/维甲酸诱导凋亡相关基因抗体
产品名称: 干扰素/维甲酸诱导凋亡相关基因抗体
英文名称: GRIM19
产品编号: bs-3594R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-01-13T10:41:03
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.