RANBP1 polyclonal antibody
产品名称： RANBP1 polyclonal antibody
英文名称： RANBP1 polyclonal antibody
产品编号： PAB6654
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of RANBP1.
- Immunogen:
- A synthetic peptide corresponding to human RANBP1.
- Sequence:
- C-LSVKEETKEDAEEKQ
- Host:
- Goat
- Theoretical MW (kDa):
- 23.3
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.1-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1.
Bischoff FR, Krebber H, Smirnova E, Dong W, Ponstingl H.EMBO J. 1995 Feb 15;14(4):705-15.
- Entrez GeneID:
- 5902
- Protein Accession#:
- NP_002873
- Gene Name:
- RANBP1
- Gene Alias:
- HTF9A,MGC88701
- Gene Description:
- RAN binding protein 1
- Omim ID:
- 601180
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq
- Other Designations:
- -
- Related Disease