Anti-GNB3 Polyclonal Antibody

品牌：solarbio | 货号：K002769P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002769P-50ul	solarbio	50ul	960.00元
K002769P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-GNB3 Polyclonal Antibody
别名	CSNB1H
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Mouse Rat
蛋白分子量	37kDa
Gene ID	2784
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human GNB3
性状	液体
Public Immunogen Range	Recombinant protein of human GNB3
Subcellular Locations	Cytosol secreted Plasma Membrane
Swiss Prot	P16520
克隆类型	Polyclonal Antibody
背景资料	Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.